GO:0045283 cellular_component fumarate reductase complex
| PAG Title | GO:0045283 cellular_component fumarate reductase complex |
| PAG ID | TAX025049 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR004224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 351 |
| Information Content | Rich |
| Other IDs | GO:0045283 |
| Base PAG ID | TAX025049 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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